Litcius/Paper detail

Chimeric kinase ALK induces expression of NAMPT and selectively depends on this metabolic enzyme to sustain its own oncogenic function

Qian Zhang, Johnvesly Basappa, Hong Y. Wang, Selene Nuñez-Cruz, Cosimo Lobello, Shengchun Wang, Xiaobin Liu, Seble Chekol, Lili Guo, Amy Ziober, Reza Nejati, Alex A. Shestov, Michael D. Feldman, Jerry D. Glickson, Suzanne D. Turner, Ian A. Blair, Chi V. Dang, Mariusz A. Wasik

2023Leukemia13 citationsDOIOpen Access PDF

Topics & Concepts

Anaplastic lymphoma kinaseCancer researchBiologyKinaseSignal transductionCell growthAnaplastic large-cell lymphomaALK inhibitorCell biologyBiochemistryLymphomaImmunologyMedicineMalignant pleural effusionPleural effusionSurgeryUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors ResearchDNA Repair Mechanisms