Litcius/Paper detail

Increased liver glycogen levels enhance exercise capacity in mice

Iliana López‐Soldado, Joan J. Guinovart, Jordi Durán

2021Journal of Biological Chemistry45 citationsDOIOpen Access PDF

Abstract

mice. Exercise-induced changes in skeletal muscle were similar in both genotypes. These results identify hepatic glycogen as a key regulator of endurance capacity in mice, an effect that may be exerted through the maintenance of blood glucose levels.

Topics & Concepts

GlycogenInternal medicineEndocrinologyGlucagonEndurance trainingSkeletal musclePhysical exerciseBiologyChemistryMedicineInsulinMuscle metabolism and nutritionAdipose Tissue and MetabolismExercise and Physiological Responses