Hybrid micelles codelivering shikonin and IDO-1 siRNA enhance immunotherapy by remodeling immunosuppressive tumor microenvironment
Ji Li, Ming Zhao, Yunhua Xu, Xiaoyun Hu, Yinghui Dai, Dongkai Wang
Topics & Concepts
ImmunosuppressionTumor microenvironmentImmunotherapyCancer researchImmune systemGene knockdownCytotoxic T cellCancer immunotherapyMedicineImmunogenic cell deathImmunologyChemistryApoptosisIn vitroBiochemistryImmune Cell Function and InteractionBioactive Compounds and Antitumor AgentsImmunotherapy and Immune Responses