SOCE-mediated NFAT1–NOX2–NLRP1 inflammasome involves in lipopolysaccharide-induced neuronal damage and Aβ generation
Zhenghao Sun, Xuewang Li, Yang Liu, Xianan Dong, Yuli Han, Yan Li, Jing Luo, Weizu Li
Topics & Concepts
ApocyninNADPH oxidaseChemistryOxidative stressInflammasomeNFATNeuroinflammationPhospholipase CCell biologyNALP3Reactive oxygen speciesInflammationSignal transductionBiologyBiochemistryTranscription factorImmunologyReceptorGeneNeuroinflammation and Neurodegeneration MechanismsAdvanced Glycation End Products researchNeutrophil, Myeloperoxidase and Oxidative Mechanisms