Coronary spasm and vasomotor dysfunction as a cause of MINOCA
Zachary S. Yaker, A. Michael Lincoff, Leslie Cho, Stephen G. Ellis, Khaled M. Ziada, Joseph J Zieminski, Rajiv Gulati, Bernard J. Gersh, David Holmes, Claire Raphael
Abstract
Increasing evidence has shown that coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) as well as an important cause of chronic chest pain in the outpatient setting. We review the contemporary understanding of coronary spasm and related vasomotor dysfunction of the coronary arteries, the pathophysiology and prognosis, and current and emerging approaches to diagnosis and evidence-based treatment.
Topics & Concepts
MedicineVasomotorCardiologyCoronary arteriesInternal medicineChest painPathophysiologyArteryCardiac Imaging and DiagnosticsAcute Myocardial Infarction ResearchCoronary Interventions and Diagnostics