BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis
Kassandra Koumaki, Georgia Kontogianni, Vivian Kosmidou, Fani Pahitsa, Eftichia Kritsi, Maria I. Zervou, Aristotelis Chatziioannou, Vassilis L. Souliotis, Olga Papadodima, Alexander Pintzas
Topics & Concepts
Cancer researchCircuit breakerMedicineEngineeringMechanical engineeringMelanoma and MAPK PathwaysCytokine Signaling Pathways and InteractionsCancer Mechanisms and Therapy