Phase I trials of the lysine-specific demethylase 1 inhibitor, GSK2879552, as mono- and combination-therapy in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes
Gail J. Roboz, Karen Yee, Amit Verma, Gautam Borthakur, Adolfo de la Fuente Burguera, Guillermo Sanz, Helai P. Mohammad, Ryan G. Kruger, Natalie O. Karpinich, Geraldine Ferron‐Brady, Andre Acusta, Heather Del Buono, Therese Collingwood, Marc Ballas, Arindam Dhar, Andrew H. Wei
Topics & Concepts
Myelodysplastic syndromesMyeloid leukemiaRefractory (planetary science)DemethylaseMedicineInternal medicineLeukemiaOncologyCancer researchBiologyGeneBone marrowBiochemistryAstrobiologyEpigeneticsEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchAcute Myeloid Leukemia Research