Defect-rich sonosensitizers based on CeO<sub>2</sub> with Schottky heterojunctions for boosting sonodynamic/chemodynamic synergistic therapy
Haiyang Zheng, Na Yin, Kehong Lv, Rui Niu, Shijie Zhou, Yinghui Wang, Hongjie Zhang
Abstract
A defect-rich hollow Schottky heterojunction sonosensitizer, constructed by defect engineering and noble metal enrichment, exhibits an amplified treatment effect for sonodynamic therapy due to the inhibition effect of electron–hole pair recombination.
Topics & Concepts
Sonodynamic therapyReactive oxygen speciesTumor microenvironmentRedoxOxygenMaterials scienceOxidative stressSchottky barrierGlutathioneTumor hypoxiaHeterojunctionChemistryBiophysicsNanotechnologyCancer researchBiochemistryOptoelectronicsInorganic chemistryTumor cellsMedicineBiologyRadiation therapyOrganic chemistryDiodeInternal medicineEnzymeNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisLuminescence Properties of Advanced Materials