Glycyrrhizin improved autophagy flux via HMGB1-dependent Akt/mTOR signaling pathway to prevent Doxorubicin-induced cardiotoxicity
Xueli Lv, Yaolu Zhu, Yingguang Deng, Shi-Chang Zhang, Qing Zhang, Boxin Zhao, Guofeng Li
Topics & Concepts
CardiotoxicityAutophagyPI3K/AKT/mTOR pathwayGlycyrrhizinDoxorubicinProtein kinase BPharmacologyChemistryCancer researchSignal transductionMedicineApoptosisToxicityBiochemistryChemotherapyInternal medicinePharmacological Effects of Natural CompoundsAutophagy in Disease and TherapySirtuins and Resveratrol in Medicine