Trilobatin rescues fulminant hepatic failure by targeting COX2: Involvement of ROS/TLR4/NLRP3 signaling
Fangqin Hou, Xiaoyu Wu, Miaoxian Gong, Jiajia Wei, Yang Yi, Yu Wei, Zhixu He, Qihai Gong, Jian-mei Gao
Topics & Concepts
LipopolysaccharideChemistryPharmacologyWestern blotOxidative stressInflammationTLR4BiochemistrySignal transductionMedicineInternal medicineGeneDrug-Induced Hepatotoxicity and ProtectionHemoglobin structure and functionInflammasome and immune disorders