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Irritable bowel syndrome: Epidemiology, overlap disorders, pathophysiology and treatment

Kai-Yue Huang, Fengyun Wang, Mi Lv, Xiangxue Ma, Xudong Tang, Lin Lv

2023World Journal of Gastroenterology141 citationsDOIOpen Access PDF

Abstract

Coronavirus disease 2019 (COVID-19) has several extrapulmonary symptoms. Gastrointestinal (GI) symptoms are among the most frequent clinical manifestations of COVID-19, with severe consequences reported in elderly patients. Furthermore, the impact of COVID-19 on patients with pre-existing digestive diseases still needs to be fully elucidated, particularly in the older population. This review aimed to investigate the impact of COVID-19 on the GI tract, liver, and pancreas in individuals with and without previous digestive diseases, with a particular focus on the elderly, highlighting the distinctive characteristics observed in this population. Finally, the effectiveness and adverse events of the anti-COVID-19 vaccination in patients with digestive disorders and the peculiarities found in the elderly are discussed.

Topics & Concepts

Irritable bowel syndromeMedicineEpidemiologyDiseaseCoronavirus disease 2019 (COVID-19)Internal medicineAdverse effectPopulationGastroenterologyGastrointestinal diseaseEnvironmental healthInfectious disease (medical specialty)Gastrointestinal motility and disordersHelicobacter pylori-related gastroenterology studiesClostridium difficile and Clostridium perfringens research
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