Proof-of-concept optimization of a copper-mediated <sup>18</sup>F-radiosynthesis of a novel MAGL PET tracer on a high-throughput microdroplet platform and its macroscale translation
Yingqing Lu, Yingfang He, Roger Schibli, Linjing Mu, R. Michael van Dam
Abstract
). The successful translation to vial-based reactions ensures wider applicability of the optimized synthesis by leveraging widely available commercial vial-based synthesis modules.
Topics & Concepts
RadiosynthesisMonoacylglycerol lipaseChemistryTRACERYield (engineering)RadiochemistryPositron emission tomographyPet imagingNuclear chemistryCombinatorial chemistryMaterials scienceNuclear medicineBiochemistryPhysicsEndocannabinoid systemMedicineNuclear physicsMetallurgyReceptorMass Spectrometry Techniques and ApplicationsInnovative Microfluidic and Catalytic Techniques InnovationAdvanced Data Storage Technologies