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In vitro to in vivo extrapolation for predicting human equivalent dose of phenolic endocrine disrupting chemicals: PBTK model development, biological pathways, outcomes and performance

Ruili Xie, Xiaodan Wang, Yiping Xu, Lei Zhang, Mei Ma, Zijian Wang

2023The Science of The Total Environment12 citationsDOI

Topics & Concepts

In vivoExtrapolationIn vitroChemistryComputational biologyPharmacologyEnvironmental chemistryBiochemical engineeringBiologyBiochemistryBiotechnologyEngineeringMathematicsMathematical analysisEffects and risks of endocrine disrupting chemicalsToxic Organic Pollutants ImpactCarcinogens and Genotoxicity Assessment
In vitro to in vivo extrapolation for predicting human equivalent dose of phenolic endocrine disrupting chemicals: PBTK model development, biological pathways, outcomes and performance | Litcius