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Microbiota-derived urocanic acid triggered by tyrosine kinase inhibitors potentiates cancer immunotherapy efficacy

Mengying Zhang, Zhonghong Wei, Bin Wei, Changjie Lai, Gangfan Zong, Enxiang Tao, Minmin Fan, Yehua Pan, Bingyan Zhou, Luping Shen, Jingjing Wu, Qingqing Wang, Ying Peng, Le Zhen, Yunhao Wu, Lu Yin, Guangji Wang, Fang Zhou, Yunlong Shan

2025Cell Host & Microbe18 citationsDOI

Topics & Concepts

Urocanic acidBiologyCancer immunotherapyImmunotherapyCancer researchKinaseCancerPharmacologyEnzymeBiochemistryGeneticsHistidineTryptophan and brain disordersTea Polyphenols and EffectsCancer, Stress, Anesthesia, and Immune Response
Microbiota-derived urocanic acid triggered by tyrosine kinase inhibitors potentiates cancer immunotherapy efficacy | Litcius