Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization
Biyan Zhang, Elise Liu, Jake A. Gertie, Julie Joseph, Lan Xu, Elisha Y. Pinker, Daniel A. Waizman, Jason Catanzaro, Kedir Hussen Hamza, Katharina Lahl, Uthaman Gowthaman, Stephanie C. Eisenbarth
Abstract
Generation of peanut-specific gut immunoglobulin A antibodies is independent of T follicular helper cells.
Topics & Concepts
ImmunologyImmunoglobulin EFollicular phaseAntibodySecretory IgASensitizationBiologyImmunoglobulin AImmunoglobulin GEndocrinologyTransgenic Plants and ApplicationsFood Allergy and Anaphylaxis ResearchCeliac Disease Research and Management