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Application of Nanomaterial in Hydrogels Related to Wound Healing

Yangyang Liu, Shurui Song, Shuangyong Liu, Xiaoyan Zhu, Peige Wang

2022Journal of Nanomaterials62 citationsDOIOpen Access PDF

Abstract

Traditional dressings used for wound repair, such as gauze, have shortcomings; for example, they cannot provide a suitable microenvironment for wound recovery. Therefore, it is necessary to find a better dressing to overcome shortcomings. Hydrogel provides a suitable wet environment, has good biocompatibility, and has a strong swelling rate to absorb exudate. Nanomaterial in hydrogels has been used to improve their performance and overcome the shortcomings of current hydrogel dressings. Hydrogel dressing can also be loaded with nanodrug particles to exert a better therapeutic effect than conventional drugs and to make the dressing more practical. This article reviews the application of nanotechnology in hydrogels related to wound healing and discusses the application prospects of nanohydrogels. After searching for hydrogel articles related to wound healing, we found that nanomaterial can not only enhance the mechanical strength, antibacterial properties, and adhesion of hydrogels but also achieve sustained drug release. From the perspective of clinical application, these characteristics are significant for wound healing. The combination of nanomaterial and hydrogel is an ideal dressing with broad application prospects for wound healing in the future.

Topics & Concepts

Self-healing hydrogelsMaterials scienceWound healingWound dressingBiocompatibilityNanomaterialsNanotechnologyBiomedical engineeringMechanical strengthComposite materialMedicineSurgeryMetallurgyPolymer chemistryWound Healing and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsSurgical Sutures and Adhesives
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