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Thermodynamics of multilayer protein adsorption on a gold nanoparticle surface

Akriti Mishra, Puspendu K. Das

2022Physical Chemistry Chemical Physics14 citationsDOI

Abstract

for the subsequent layers indicate that ADH, BSA, and insulin are all physiosorbed on the GNP surface. The temperature dependent DLS data point out that the adsorption of these proteins on GNPs is endothermic but is accompanied by a large increase in entropy. The nature of the BET fits to the adsorption data shows that multilayer adsorption starts even before the monolayer formation is complete, and it does not occur in a layer-by-layer sequence.

Topics & Concepts

AdsorptionMonolayerChemistryProtein adsorptionBovine serum albuminColloidal goldNanoparticleDynamic light scatteringZeta potentialLangmuirLangmuir adsorption modelGibbs isothermAnalytical Chemistry (journal)CrystallographyChemical engineeringChromatographyPhysical chemistryBiochemistryEngineeringProtein Interaction Studies and Fluorescence AnalysisGold and Silver Nanoparticles Synthesis and ApplicationsPolymer Surface Interaction Studies
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