Remote C(sp<sup>3</sup>)–H heteroarylation of <i>N</i>-fluorocarboxamides with quinoxalin-2(1<i>H</i>)-ones under visible-light-induced photocatalyst-free conditions
Liangming Xuan, Ruyang Du, Panpan Lei, Wei Zhao, Lixiang Tan, Chuanzhi Ni, Haifeng Wang, Qiongjiao Yan, Wei Wang, Fen‐Er Chen
Abstract
A photocatalyst-free visible-light-promoted remote C(sp 3 )–H heteroarylation of N -fluoroamides with quinoxalin-2(1 H )-ones was developed. All types of δ-C(sp 3 )–H bonds in the N -fluoroamides could be site-specific activated through the 1,5-HAT process.
Topics & Concepts
Visible spectrumPhotocatalysisPhotochemistryChemistryMaterials scienceOptoelectronicsCatalysisOrganic chemistryCatalytic C–H Functionalization MethodsFluorine in Organic ChemistryRadical Photochemical Reactions