BAX mitochondrial integration is regulated allosterically by its α1−α2 loop
Michael A. Dengler, Leonie Gibson, Jerry M. Adams
Topics & Concepts
Allosteric regulationCell biologyBiologyMutagenesisBcl-2-associated X proteinTransmembrane proteinLoop (graph theory)MutationProgrammed cell deathMitochondrionAlanineTransmembrane domainChemistryApoptosisMolecular biologyBiochemistryGeneAmino acidReceptorCaspase 3MathematicsCombinatoricsCell death mechanisms and regulationRNA Interference and Gene DeliveryMitochondrial Function and Pathology