Bictegravir Use During Pregnancy: A Multicenter Retrospective Analysis Evaluating HIV Viral Suppression and Perinatal Outcomes
Lauren Holt, William R. Short, Florence Momplaisir, Eleanor Hyun, Jennifer McKinney, Andrea Lugo Morales, Alejandra Duque, Brian Zachary Druyan, Chima Ndubizu, Luthita Duthely, Naima T. Joseph, Anandi N. Sheth, Martina L. Badell
Abstract
This study describes the largest cohort to date (n = 147) of pregnant patients with human immunodeficiency virus (HIV) on bictegravir (BIC). BIC in pregnancy was associated with high levels of viral suppression and perinatal outcomes similar to those in the published literature. These findings support consideration for the use of BIC in managing HIV during pregnancy.
Topics & Concepts
MedicinePregnancyHuman immunodeficiency virus (HIV)Retrospective cohort studyObstetricsCohort studySidaGynecologyViral diseaseVirologyInternal medicineGeneticsBiologyHIV-related health complications and treatmentsHIV/AIDS Research and InterventionsHIV/AIDS drug development and treatment