CRISPR/Cas12a collateral cleavage activity for simple and rapid detection of protein/small molecule interaction
Hansol Kim, Seoyoung Lee, Junhyeok Yoon, Jayeon Song, Hyun Gyu Park
Topics & Concepts
CRISPRTrans-activating crRNADigoxigeninSmall moleculeChemistryComputational biologyDNAStreptavidinCleavage (geology)Molecular probeBiophysicsCas9BiologyBiotinBiochemistryMessenger RNAGeneFracture (geology)In situ hybridizationPaleontologyCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanisms