Litcius/Paper detail

Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors

Yuru Liang, Mao Zhang, Pengfei Zhou, Mingming Liu, Jianqi Li, Yang Wang

2021Bioorganic Chemistry16 citationsDOI

Topics & Concepts

ChemistryIn vitroApoptosisTubulinSubstituentStereochemistryArylIntracellularCell cycleMicrotubulePharmacologyBiochemistryCell biologyOrganic chemistryBiologyAlkylSynthesis of β-Lactam CompoundsPhytochemical compounds biological activitiesMicrobial Natural Products and Biosynthesis