Safety, efficacy, and tolerability of memantine for cognitive and adaptive outcome measures in adolescents and young adults with Down syndrome: a randomised, double-blind, placebo-controlled phase 2 trial
Alberto C S Costa, Ana C Brandão, Richard Boada, Veridiana L Barrionuevo, Hudson G Taylor, Elizabeth Roth, Melissa R Stasko, Mark W Johnson, Fernanda F Assir, Maria P Roberto, Patrícia Salmona, Guilherme Abreu-Silveira, Ilya Bederman, Erin Prendergast, Anke Hüls, Sarina Abrishamcar, Zan Mustacchi, Thomas Scheidemantel, Nancy J Roizen, Stephen Ruedrich
Topics & Concepts
Young adultMedicineCognitionTolerabilityMemantineOutcome (game theory)Context (archaeology)PediatricsClinical trialPortuguesePhase (matter)PsychiatryPhysical therapyRandomized controlled trialEffects of sleep deprivation on cognitive performanceInternal medicineDown syndrome and intellectual disability researchAttention Deficit Hyperactivity DisorderBehavioral and Psychological Studies