KAT8/MOF-Mediated Anti-Cancer Mechanism of Gemcitabine in Human Bladder Cancer Cells
Huihui Zhu, Yong Wang, Tao Wei, Xiaoming Zhao, Fuqiang Li, Yana Li, Fei Wang, Yong Cai, Jingji Jin
Abstract
experiments, the additive effects on cell proliferation and migration were observed in the presence of exogenous MOF and GEM. In addition, the promoted cell sensitivity to GEM by exogenous MOF in BLCA cells was confirmed using an Annexin V-FITC/PI assay. Taken together, our results provide the theoretical basis for elucidating the anti-BLCA mechanism of GEM.
Topics & Concepts
GemcitabineBladder cancerMedicineCancerCancer cellHuman bladderMechanism (biology)Cancer researchPharmacologyInternal medicinePhilosophyEpistemologyHistone Deacetylase Inhibitors ResearchEpigenetics and DNA MethylationPeptidase Inhibition and Analysis