Thiamine carbene liganded gold(<scp>i</scp>) chloride catalyzes an efficient aldehyde–alkyne–amine coupling reaction in water
Rajashekar Reddy Narra, Vignesh Gopalakrishnan Unnithan, Ting Hei Wong, Zhihong Guo
Abstract
Thiamine (vitamin B1) carbene liganded gold( i ) chloride efficiently catalyses an aldehyde–alkyne–amine (A 3 ) coupling reaction in open air under solvent-free conditions or in water.
Topics & Concepts
AlkyneThiamineChemistryAldehydeAmine gas treatingCarbeneChlorideSolventCoupling reactionCatalysisCombinatorial chemistryOrganic chemistryPhotochemistryCatalytic Alkyne ReactionsCyclopropane Reaction MechanismsCatalytic Cross-Coupling Reactions