Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors
Jonas Becker, Megan L. Stanifer, Sarah R. Leist, Bettina Stolp, Olena Maiakovska, Ande West, Ellen Wiedtke, Kathleen Börner, Ali Ghanem, Ina Ambiel, Longping V. Tse, O. Fackler, Ralph S. Baric, Steeve Boulant, Dirk Grimm
Topics & Concepts
VirologyBiologyRNA interferenceSmall hairpin RNAVector (molecular biology)VirusCoronavirusMedicineDiseaseCoronavirus disease 2019 (COVID-19)GeneGene knockdownGeneticsRNAInfectious disease (medical specialty)Recombinant DNAPathologyVirus-based gene therapy researchSARS-CoV-2 and COVID-19 ResearchRNA Interference and Gene Delivery