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P–C Bond Cleavage Induced Ni(II) Complexes Bearing Rare-Earth-Metal-Based Metalloligand and Reactivities toward Isonitrile, Nitrile, and Epoxide

Peng Cui, Xia Huang, Jun Du, Zeming Huang

2021Inorganic Chemistry20 citationsDOI

Abstract

Protonolysis of β-diketiminato (nacnac) rare-earth metal bis-alkyl complexes LnacnacLnR2(THF) (Ln = Y and Lu) with 2 equiv of Ph2PNHPh or Ph2PCH2NHPh afforded the bis-amido complexes LnacnacY(Ph2PNPh)2 and LnacnacLn(Ph2PCH2NPh)2 (Ln = Y and Lu). Metalation of the latter complexes with 1 equiv of Ni(COD)2 led to the isolation of unusual heterobimetallic Ni(II)–Ln(III) complexes formed via P–C bond cleavage of one [Ph2PCH2NPh]− ligand. Notably, both the imine PhN═CH2 and phosphide Ph2P– fragments from the P–C bond cleavage were trapped in the Ni(II)–Ln(III) core with a relatively weak interaction between the two metal centers. The Ni(II)–Y(III) complex have exhibited versatile reactivity, such as coordination of isonitrile to the Ni(II) center, insertion of nitrile with the coordinated imine, and ring-opening of the epoxide by nucleophilic attack from the phosphide group.

Topics & Concepts

ChemistryNitrileBond cleavageMedicinal chemistryPhosphideNucleophileImineStereochemistryLigand (biochemistry)EpoxideCleavage (geology)ProtonolysisReactivity (psychology)MetalAlkylMetalationOrganic chemistryCatalysisAlternative medicineReceptorPathologyFracture (geology)MedicineBiochemistryGeotechnical engineeringEngineeringOrganometallic Complex Synthesis and CatalysisMetalloenzymes and iron-sulfur proteinsFerrocene Chemistry and Applications
P–C Bond Cleavage Induced Ni(II) Complexes Bearing Rare-Earth-Metal-Based Metalloligand and Reactivities toward Isonitrile, Nitrile, and Epoxide | Litcius