Pd-Catalyzed Indole Synthesis via C–H Activation and Bisamination Sequence with Diaziridinone
Jianjun Wang, Xiao‐Feng Sun, Daguo Hu, Yian Shi
Abstract
This work describes an efficient Pd-catalyzed indole synthesis. A wide variety of indoles can be obtained in good yields from readily available vinyl bromides. The reaction likely proceeds through a sequential aryl C-H activation and bisamination of a resulting pallada(II)cycle with diaziridinone.
Topics & Concepts
ChemistryIndole testCatalysisSequence (biology)Combinatorial chemistryStereochemistryMedicinal chemistryOrganic chemistryBiochemistryCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsCatalytic Cross-Coupling Reactions