Berberine chloride suppresses non-small cell lung cancer by deregulating Sin3A/TOP2B pathway in vitro and in vivo
Jian Chen, Xiaofei Huang, Cheng Tao, Li Wang, Zide Chen, Xinping Li, Qiang Zeng, Min Ma, Ren Zhang, Zhengzhi Wu
Topics & Concepts
Downregulation and upregulationApoptosisBiologyGene knockdownCancer researchIn vivoIn vitroSmall interfering RNACell biologyTransfectionA549 cellDNA damageMolecular biologyCell cultureGeneDNABiochemistryGeneticsBerberine and alkaloids researchSynthesis and Biological ActivityPhytochemical Studies and Bioactivities