Single-cell analysis reveals cell death as driver of NLRP3-mediated secretion of IL-1β in human monocytes
Lieselotte Vande Walle, Kentaro Kato, Mai Yamagishi, Takashi Kamatani, Alex Vervaeke, Rosa Martín‐Pérez, Masaki Shimizu, Takumi Takizawa, Junko Takita, Ryuta Nishikomori, Osamu Ohara, Kazushi Izawa, Yoshitaka Shirasaki, Mohamed Lamkanfi
Topics & Concepts
PyroptosisSecretionInflammasomeProinflammatory cytokineLytic cycleCell biologyFlow cytometryProgrammed cell deathBiologyInflammationImmunologyCytokineCaspase 1ApoptosisCellMonocyteChemistryCell typePhenotypeInterleukinAIM2Inflammasome and immune disordersStreptococcal Infections and TreatmentsImmune Response and Inflammation