Sp1-mediated upregulation of Prdx6 expression prevents podocyte injury in diabetic nephropathy via mitigation of oxidative stress and ferroptosis
Qian-Jin Zhang, Yichuan Hu, Jin-E Hu, Ying Ding, Yanqiu Shen, Hong Xu, Huiqin Chen, Ning Wu
Topics & Concepts
PodocyteDownregulation and upregulationDiabetic nephropathyOxidative stressCell biologyChemistryTransfectionGene silencingCancer researchViability assayCellDiabetes mellitusEndocrinologyBiologyKidneyBiochemistryGeneProteinuriaSelenium in Biological SystemsFerroptosis and cancer prognosisGlutathione Transferases and Polymorphisms