Litcius/Paper detail

Morphology, Solid Structure and Antioxidant Activity <i>in Vitro</i> of <i>Angelica sinensis</i> Polysaccharide‐Ce(IV)

Kaiwen Li, Jie Wang, Zizhen Huang, Chunxia Tan

2023Chemistry & Biodiversity12 citationsDOI

Abstract

Abstract Angelica Sinensis polysaccharide cerium (ASP−Ce) was prepared by Angelica Sinensis polysaccharide (ASP) and cerium ammonium nitrate (NH 4 ) 2 Ce(NO 3 ) 6 . and its morphology, and solid structure was investigated. The antioxidant activity of the ASP−Ce complex in vitro was evaluated. The antioxidant activity of ASP−Ce complex in vitro was evaluated by the scavenging activity of 2,2‐diphenyl‐1‐picrylhyrazyl radical (DPPH), hydroxyl radical (⋅OH) and superoxide anion radical ( ⋅). The results showed that the ASP−Ce had the more ordered structure for inserting the Ce 4+ into the polymer chain of ASP and there was little change in the conformation of the polysaccharide from Ce 4+ . Three free radical scavenging experiments proved that ASP−Ce had better antioxidant capacity than of ASP, especially on DPPH, and then on ⋅. The scavenging rate of ASP−Ce at 1.0 mg/mL on DPPH reached 71.6 %. Therefore, these results provide references for the further development and utilization of rare earth‐polysaccharide.

Topics & Concepts

ChemistryDPPHAntioxidantCeriumPolysaccharideAngelica sinensisSuperoxideHydroxyl radicalAmmonium nitrateIn vitroNuclear chemistryOrganic chemistryBiochemistryEnzymeTraditional Chinese medicineMedicineAlternative medicinePathologyGeochemistry and Elemental AnalysisChromium effects and bioremediationAdvanced Nanomaterials in Catalysis