Electrochemical Synthesis of 5‐Selenouracil Derivatives by Selenylation of Uracils
Qian Wang, Xian‐Li Ma, Yanyan Chen, Caina Jiang, Yanli Xü
Abstract
A simple and efficient electrochemical selenylation of uracils in the presence of NH 4 I for the synthesis of 5‐selenouracils has been developed. This transformation was performed in the transition metal‐free, oxidant‐free, and aerobic conditions, providing a rapid and practical protocol to 5‐selenouracil derivatives.
Topics & Concepts
ChemistryElectrochemistryTransformation (genetics)Combinatorial chemistryPhysical chemistryElectrodeBiochemistryGeneSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsOrganoselenium and organotellurium chemistry