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Sexual dimorphism in functional pain syndromes

Edita Navratilova, Roger B. Fillingim, Frank Porreca

2021Science Translational Medicine22 citationsDOIOpen Access PDF

Abstract

Injury-free pain conditions, defined as functional pain syndromes, are more prevalent and more disabling in women. Mechanisms of sexual dimorphism in functional pain are now emerging from preclinical studies, suggesting an opportunity to advance the development of sex-specific therapies that may improve treatment of pain in women.

Topics & Concepts

Sexual dimorphismPain syndromeChronic painMedicineSex characteristicsBioinformaticsPhysical therapyBiologyInternal medicineMusculoskeletal pain and rehabilitationFibromyalgia and Chronic Fatigue Syndrome ResearchPain Mechanisms and Treatments
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