Investigation on chloro-bridged binuclear copper(<scp>ii</scp>) complexes as potent metallodrug candidates against colon cancer <i>via</i> chemical and biological assessments
K.S. Neethu, Badhmapriya Devarajan, Akilesh Manimuthu, Nattamai Bhuvanesh, Nallasamy Dharmaraj, Kaveri M. Velusamy
Abstract
Synthesized binuclear copper( ii ) complexes have been utilized for catechol oxidase mimicking activity, DNA/BSA interactions, molecular docking and pharmacological potential assessment against colon cancer and normal skin cells through in vitro method.
Topics & Concepts
ChemistryCopperStereochemistryColorectal cancerCombinatorial chemistryCancerOrganic chemistryInternal medicineMedicineMetal complexes synthesis and propertiesTrace Elements in HealthOrganometallic Compounds Synthesis and Characterization