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Anti-obesity effects of capsaicin and the underlying mechanisms: a review

Run Li, Yaqi Lan, Chengyu Chen, Yong Cao, Qingrong Huang, Chi‐Tang Ho, Muwen Lu

2020Food & Function91 citationsDOI

Abstract

Obesity and overweight have become serious health problems in the world and are linked to a variety of metabolic disorders. Phytochemicals with a weight-loss effect have been widely studied for the past few decades. Capsaicin is the major bioactive component in red chili peppers with many beneficial functions. Its anti-obesity effects have been evaluated extensively using different model systems, including cell models, animal models and human subjects. In this paper, anti-obesity effects of capsaicin are reviewed and the underlying mechanisms are characterized.

Topics & Concepts

CapsaicinObesityNeuroscienceRodentPharmacologyMedicinePsychologyInternal medicineBiologyReceptorEcologyAdipose Tissue and MetabolismBiochemical Analysis and Sensing TechniquesSirtuins and Resveratrol in Medicine