RUNX1 regulates SMAD1 by transcriptionally activating the expression of USP9X, regulating the activation of hepatic stellate cells and liver fibrosis
Jie Huang, Yan Li, Dingwei Xu, Xiao Zhang, Xiaoyang Zhou
Topics & Concepts
Hepatic stellate cellTranscription factorMolecular biologyViability assayGene knockdownGene silencingSirius RedBiologyCancer researchChromatin immunoprecipitationCell biologyGene expressionCell culturePromoterImmunologyCellEndocrinologyBiochemistryImmunohistochemistryGeneGeneticsLiver physiology and pathologyHepatitis B Virus StudiesUbiquitin and proteasome pathways