Synthesis, molecular docking, dynamic simulation and pharmacological characterization of potent multifunctional agent (dual GPR40-PPARγ agonist) for the treatment of experimental type 2 diabetes
Sergio Hidalgo‐Figueroa, Ana Rodríguez-Luévano, Julio Cesar Almanza-Pérez, Abraham Giacoman‐Martínez, Rolffy Ortíz‐Andrade, Ismael León‐Rivera, Gabriel Navarrete‐Vázquez
Topics & Concepts
Free fatty acid receptor 1AgonistReceptorGLUT4ChemistryDocking (animal)PharmacologyPeroxisome proliferator-activated receptorEndocrinologyInternal medicineInsulinBiochemistryInsulin resistanceBiologyMedicineNursingPeroxisome Proliferator-Activated ReceptorsDiabetes Treatment and ManagementMetabolism, Diabetes, and Cancer