SUB1 promotes colorectal cancer metastasis by activating NF-κB signaling via UBR5-mediated ubiquitination of UBXN1
Hao Wang, Wenwen Chen, Yanting Wang, Yuzhen Gao, Zizhen Zhang, Shuyi Mi, Liangjing Wang, Meng Xue
Topics & Concepts
Ubiquitin ligaseCancer researchUbiquitinMetastasisColorectal cancerNF-κBSignal transductionCoactivatorBiologyCancerChemistryMedicineTranscription factorCell biologyInternal medicineBiochemistryGeneUbiquitin and proteasome pathwaysCancer-related molecular mechanisms researchRNA modifications and cancer