Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion
Lele Zhang, Ke Ding, Shi-shi Liao, Yi-guo Zhang, Hui-yang Liao, Rong Chen, Qingtao Meng
Topics & Concepts
KEAP1mTORC1Gene knockdownReperfusion injuryReactive oxygen speciesIschemiaSignal transductionCancer researchCell biologyChemistryPharmacologyBiologyMedicineBiochemistryPI3K/AKT/mTOR pathwayGeneInternal medicineTranscription factorCancer, Lipids, and MetabolismCholesterol and Lipid MetabolismFerroptosis and cancer prognosis