Variants of Concern responsible for SARS-CoV-2 vaccine breakthrough infections from India
Urvashi B. Singh, Mercy Rophina, Rama Chaudhry, Vigneshwar Senthivel, Kiran Bala, Rahul C. Bhoyar, Bani Jolly, Nayer Jamshed, Mohamed Imran, Ritu Gupta, Praveen Aggarwal, Mohit Kumar Divakar, Subrata Sinha, Arvinden V.R., Anjali Bajaj, Afra Shamnath, Abhinav Jain, COVID CBNAAT CORE GROUP, Vinod Scaria, Sridhar Sivasubbu, Randeep Guleria
Abstract
Emerging reports of SARS-CoV-2 breakthrough infections entail methodical genomic surveillance for determining efficacy of vaccines. This study elaborates genomic analysis of isolates from breakthrough infections following vaccination with AZD1222/Covishield and BBV152/Covaxin.Variants of concern B.1.617.2 and B.1.1.7 responsible for cases surge in April-May 2021 in Delhi, were the predominant lineages among breakthrough infections.