EGFR activation-induced decreases in claudin1 promote MUC5AC expression and exacerbate asthma in mice
Zhirong Jia, Kaifan Bao, Wei Pan, Xuerui Yu, Yuheng Zhang, Xiaotong Wang, Xiaoyu Wang, Lu Yao, Lianqu Li, Peng Wu, Weiyuan Yuan, Siqi Wang, Jie Zheng, Yongqing Hua, Min Hong
Topics & Concepts
Gene knockdownMucusGoblet cellAsthmaAmphiregulinInflammationHouse dust miteEpidermal growth factor receptorMedicineImmunologyOvalbuminCancer researchReceptorBiologyInternal medicineEpitheliumPathologyAllergyCell cultureGeneticsEcologyImmune systemAllergenBarrier Structure and Function StudiesGut microbiota and healthBerberine and alkaloids research