Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair
Jonathan J. Wilde, Tomomi Aida, Ricardo C.H. del Rosario, Tobias Kaiser, Peimin Qi, Martin Wienisch, Qiangge Zhang, Steven M. Colvin, Guoping Feng
Topics & Concepts
BiologyZygoteSomatic cellEmbryoEmbryonic stem cellGeneticsRAD51AlleleGeneCell biologyHomologous recombinationMechanism (biology)Gene conversionEmbryogenesisEpistemologyPhilosophyCRISPR and Genetic EngineeringPluripotent Stem Cells ResearchChromosomal and Genetic Variations