LOAd703, an oncolytic virus-based immunostimulatory gene therapy, combined with chemotherapy for unresectable or metastatic pancreatic cancer (LOKON001): results from arm 1 of a non-randomised, single-centre, phase 1/2 study
Benjamin Musher, Eric K. Rowinsky, Brandon G. Smaglo, Wasif M. Abidi, Mohamed O. Othman, Kalpesh Patel, Salmaan Jawaid, James Jing, Amanda Brisco, Ann M. Leen, Meng-Fen Wu, Linda C. Sandin, Jessica Wenthe, Emma Eriksson, Gustav Ullenhag, Bambi Grilley, Justyna Leja-Jarblad, Susan G. Hilsenbeck, Malcolm K. Brenner, Angelica Loskog
Topics & Concepts
MedicineGemcitabinePancreatic cancerOncolytic virusFOLFIRINOXInternal medicineClinical endpointOncologyChemotherapyCancerOncolytic adenovirusPhases of clinical researchGastroenterologyClinical trialIrinotecanColorectal cancerVirus-based gene therapy researchCancer Research and TreatmentsImmunotherapy and Immune Responses