Harnessing lipid nanoparticles for efficient CRISPR delivery
Jinyue Yan, Diana D. Kang, Yizhou Dong
Abstract
remains challenging due to the multiple extracellular and intracellular barriers. Here, we discuss the recent advances in novel lipid nanomaterials for CRISPR delivery and describe relevant examples of potential therapeutics in cancers, genetic disorders, and infectious diseases.
Topics & Concepts
CRISPRComputational biologyIn vivoNanotechnologyChemistryBiologyBiotechnologyGeneBiochemistryMaterials scienceCRISPR and Genetic EngineeringRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques