CytoMAP: A Spatial Analysis Toolbox Reveals Features of Myeloid Cell Organization in Lymphoid Tissues
Caleb Stoltzfus, Jakub Filipek, Benjamin H. Gern, Brandy Olin, Joseph M. Leal, Yajun Wu, Miranda R. Lyons‐Cohen, Jessica Huang, Clarissa L. Paz-Stoltzfus, Courtney R. Plumlee, Thomas Pöschinger, Kevin B. Urdahl, Mario Perro, Michael Y. Gerner
Abstract
dermal DCs, and preferential association of resident DCs with select LN vasculature. The findings provide insights into the organization of myeloid cells in LNs and demonstrate that CytoMAP is a comprehensive analytics toolbox for revealing features of tissue organization in imaging datasets.
Topics & Concepts
BiologyCompartmentalization (fire protection)Computational biologyMyeloidCluster analysisCell biologyCellular architectureCellNeuroscienceComputer scienceImmunologyGeneticsArtificial intelligenceReference architectureProgramming languageEnzymeSoftware architectureSoftwareBiochemistrySingle-cell and spatial transcriptomicsImmunotherapy and Immune ResponsesCell Image Analysis Techniques