Ivermectin confers its cytotoxic effects by inducing AMPK/mTOR-mediated autophagy and DNA damage
Ping Zhang, Hongfei Ni, Yang Zhang, Wenping Xu, Jufang Gao, Jiagao Cheng, Liming Tao
Topics & Concepts
AMPKPI3K/AKT/mTOR pathwayGenotoxicityAutophagyDNA damageHeLaCytotoxicityBiologyPharmacologyChemistryCell biologySignal transductionToxicityIn vitroApoptosisBiochemistryDNAPhosphorylationProtein kinase AOrganic chemistryParasitic infections in humans and animalsParasitic Infections and DiagnosticsParasitic Diseases Research and Treatment