Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Second-Line Treatment of Patients With NSCLC: Results From an Expansion Cohort of a Phase 1 Trial
Luis Paz‐Ares, Tae Min Kim, David Vicente, Enriqueta Felip, Dae Ho Lee, Ki Hyeong Lee, Chia‐Chi Lin, M.J. Flor, Massimo Di Nicola, Rosa Álvarez, Isabelle Dussault, Christoph Helwig, Laureen S. Ojalvo, James L. Gulley, Byoung Chul Cho
Topics & Concepts
MedicineInternal medicineOncologyCohortAdjuvantSorafenibGastroenterologyAdverse effectClinical endpointResponse Evaluation Criteria in Solid TumorsTolerabilityPhases of clinical researchRandomized controlled trialClinical trialHepatocellular carcinomaTGF-β signaling in diseasesCancer Immunotherapy and BiomarkersColorectal and Anal Carcinomas