Sex-related differences in the relationship between β-amyloid and cognitive trajectories in older adults.
Cutter A. Lindbergh, Hillblom Aging Network, Kaitlin B. Casaletto, Adam M. Staffaroni, Renaud La Joie, Leonardo Iaccarino, Lauren Edwards, Elena Tsoy, Fanny M. Elahi, Samantha Walters, Devyn L. Cotter, Michelle You, Alexandra C. Apple, Breton M. Asken, John Neuhaus, Jessica E. Rexach, Kevin Wojta, Gil D. Rabinovici, Joel H. Kramer
Abstract
Clinically normal women with elevated Aβ are more vulnerable to episodic memory decline than men. Understanding sex-related differences in AD, particularly in preclinical stages, is crucial for guiding precision medicine approaches to early detection and intervention. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Topics & Concepts
Episodic memoryCognitive declineCognitionPsychologyAlzheimer's Disease Neuroimaging InitiativePittsburgh compound BMedicineEffects of sleep deprivation on cognitive performanceInternal medicineDiseaseAlzheimer's diseaseDementiaPsychiatryDementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsFunctional Brain Connectivity Studies