InI <sub>3</sub> -catalyzed polyene cyclization of allenes and its application in the total synthesis of seven abietane-type diterpenoids
Chen-Yu Huo, Tian-Lu Zheng, Wei-Hao Dai, Zi-Hao Zhang, Jinda Wang, Dao‐Yong Zhu, Shao‐Hua Wang, Xiao‐Ming Zhang, Xue-Tao Xu
Abstract
A polyene cyclization mode using the allene group as the initiator has been successfully developed, and its potential utility has been well demonstrated by the collective synthesis of seven abietane-type diterpenoids.
Topics & Concepts
AbietanePolyeneCatalysisChemistryStereochemistryDiterpeneOrganic chemistryBiological Activity of Diterpenoids and BiflavonoidsSynthetic Organic Chemistry MethodsNatural product bioactivities and synthesis